ID   RM15_HUMAN              Reviewed;         296 AA.
AC   Q9P015; Q96Q54; Q9H0Y1;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   05-OCT-2010, entry version 69.
DE   RecName: Full=39S ribosomal protein L15, mitochondrial;
DE            Short=L15mt;
DE            Short=MRP-L15;
DE   Flags: Precursor;
GN   Name=MRPL15; ORFNames=HSPC145;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Blood;
RX   MEDLINE=20499367; PubMed=11042152; DOI=10.1101/gr.140200;
RA   Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G.,
RA   Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W.,
RA   Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.;
RT   "Cloning and functional analysis of cDNAs with open reading frames for
RT   300 previously undefined genes expressed in CD34+ hematopoietic
RT   stem/progenitor cells.";
RL   Genome Res. 10:1546-1560(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Fetal brain;
RX   MEDLINE=21154917; PubMed=11230166; DOI=10.1101/gr.GR1547R;
RA   Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S.,
RA   Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H.,
RA   Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N.,
RA   Mewes H.-W., Ottenwaelder B., Obermaier B., Tampe J., Heubner D.,
RA   Wambutt R., Korn B., Klein M., Poustka A.;
RT   "Towards a catalog of human genes and proteins: sequencing and
RT   analysis of 500 novel complete protein coding human cDNAs.";
RL   Genome Res. 11:422-435(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.;
RT   "Cloning of human full open reading frames in Gateway(TM) system entry
RT   vector (pDONR201).";
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Cervix;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 259-296.
RX   MEDLINE=21429115; PubMed=11543634; DOI=10.1006/geno.2001.6622;
RA   Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S.,
RA   Watanabe K., Tanaka T.;
RT   "The human mitochondrial ribosomal protein genes: mapping of 54 genes
RT   to the chromosomes and implications for human disorders.";
RL   Genomics 77:65-70(2001).
RN   [6]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RA   Colinge J., Superti-Furga G., Bennett K.L.;
RL   Submitted (OCT-2008) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion (By similarity).
CC   -!- SIMILARITY: Belongs to the ribosomal protein L15P family.
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DR   EMBL; AF161494; AAF29109.1; -; mRNA.
DR   EMBL; AL136665; CAB66600.1; -; mRNA.
DR   EMBL; CR533531; CAG38562.1; -; mRNA.
DR   EMBL; BC000891; AAH00891.1; -; mRNA.
DR   EMBL; AB051619; BAB54947.1; -; Genomic_DNA.
DR   IPI; IPI00023086; -.
DR   RefSeq; NP_054894.1; -.
DR   UniGene; Hs.18349; -.
DR   ProteinModelPortal; Q9P015; -.
DR   SMR; Q9P015; 24-175.
DR   STRING; Q9P015; -.
DR   PhosphoSite; Q9P015; -.
DR   PeptideAtlas; Q9P015; -.
DR   PRIDE; Q9P015; -.
DR   Ensembl; ENST00000260102; ENSP00000260102; ENSG00000137547.
DR   GeneID; 29088; -.
DR   KEGG; hsa:29088; -.
DR   UCSC; uc003xsa.2; human.
DR   CTD; 29088; -.
DR   GeneCards; GC08P055097; -.
DR   H-InvDB; HIX0007508; -.
DR   HGNC; HGNC:14054; MRPL15.
DR   MIM; 611828; gene.
DR   PharmGKB; PA30944; -.
DR   eggNOG; prNOG15992; -.
DR   HOGENOM; HBG384830; -.
DR   HOVERGEN; HBG088294; -.
DR   InParanoid; Q9P015; -.
DR   OMA; RRQYQPL; -.
DR   OrthoDB; EOG9PG8M3; -.
DR   PhylomeDB; Q9P015; -.
DR   NextBio; 52090; -.
DR   ArrayExpress; Q9P015; -.
DR   Bgee; Q9P015; -.
DR   CleanEx; HS_MRPL15; -.
DR   Genevestigator; Q9P015; -.
DR   GermOnline; ENSG00000137547; Homo sapiens.
DR   GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR   GO; GO:0005739; C:mitochondrion; IDA:LIFEdb.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR005749; Ribosomal_L15_bac-type.
DR   InterPro; IPR021131; Ribosomal_L18e/L15.
DR   PANTHER; PTHR12934; Ribosom_L15_bac; 1.
DR   Pfam; PF00828; Ribosomal_L18e; 1.
DR   SUPFAM; SSF52080; Ribosomal_L18e/L15; 1.
DR   TIGRFAMs; TIGR01071; rplO_bact; 1.
DR   PROSITE; PS00475; RIBOSOMAL_L15; FALSE_NEG.
PE   1: Evidence at protein level;
KW   Complete proteome; Mitochondrion; Ribonucleoprotein;
KW   Ribosomal protein; Transit peptide.
FT   TRANSIT       1     21       Mitochondrion (By similarity).
FT   CHAIN        22    296       39S ribosomal protein L15, mitochondrial.
FT                                /FTId=PRO_0000257838.
FT   COMPBIAS     38     64       Arg-rich.
FT   CONFLICT     96     96       L -> M (in Ref. 2; CAB66600 and 3;
FT                                CAG38562).
FT   CONFLICT    137    137       G -> D (in Ref. 2; CAB66600 and 3;
FT                                CAG38562).
SQ   SEQUENCE   296 AA;  33420 MW;  D7396086F808A72C CRC64;
     MAGPLQGGGA RALDLLRGLP RVSLANLKPN PGSKKPERRP RGRRRGRKCG RGHKGERQRG
     TRPRLGFEGG QTPFYIRIPK YGFNEGHSFR RQYKPLSLNR LQYLIDLGRV DPSQPIDLTQ
     LVNGRGVTIQ PLKRDYGVQL VEEGADTFTA KVNIEVQLAS ELAIAAIEKN GGVVTTAFYD
     PRSLDIVCKP VPFFLRGQPI PKRMLPPEEL VPYYTDAKNR GYLADPAKFP EARLELARKY
     GYILPDITKD ELFKMLCTRK DPRQIFFGLA PGWVVNMADK KILKPTDENL LKYYTS
//