ID   KLF14_HUMAN             Reviewed;         323 AA.
AC   Q8TD94; Q19A42; Q19A43;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   05-OCT-2010, entry version 67.
DE   RecName: Full=Krueppel-like factor 14;
DE   AltName: Full=Basic transcription element-binding protein 5;
DE            Short=BTE-binding protein 5;
DE   AltName: Full=Transcription factor BTEB5;
GN   Name=KLF14; Synonyms=BTEB5;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Kaczynski J.A., Urrutia R.A.;
RT   "Identification of BTEB5, a new member of the BTEB subfamily of Sp1-
RT   like proteins.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RA   Parker-Katiraee L., Scherer S.W.;
RT   "The centre for applied genomics genome annotation project.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-237, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Cervix carcinoma;
RX   PubMed=17924679; DOI=10.1021/pr070152u;
RA   Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
RT   "Improved titanium dioxide enrichment of phosphopeptides from HeLa
RT   cells and high confident phosphopeptide identification by cross-
RT   validation of MS/MS and MS/MS/MS spectra.";
RL   J. Proteome Res. 6:4150-4162(2007).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- SIMILARITY: Belongs to the Sp1 C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 3 C2H2-type zinc fingers.
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DR   EMBL; AF490374; AAM08349.1; -; mRNA.
DR   EMBL; DQ534756; ABF82392.1; -; Genomic_DNA.
DR   EMBL; DQ534757; ABF82393.1; -; mRNA.
DR   IPI; IPI00152493; -.
DR   RefSeq; NP_619638.1; -.
DR   UniGene; Hs.125240; -.
DR   ProteinModelPortal; Q8TD94; -.
DR   SMR; Q8TD94; 195-277.
DR   PRIDE; Q8TD94; -.
DR   Ensembl; ENST00000310992; ENSP00000310878; ENSG00000174595.
DR   GeneID; 136259; -.
DR   KEGG; hsa:136259; -.
DR   UCSC; uc003vqk.1; human.
DR   CTD; 136259; -.
DR   GeneCards; GC07M130417; -.
DR   HGNC; HGNC:23025; KLF14.
DR   MIM; 609393; gene.
DR   PharmGKB; PA134868089; -.
DR   HOGENOM; HBG403112; -.
DR   HOVERGEN; HBG050746; -.
DR   InParanoid; Q8TD94; -.
DR   OMA; VCAPESS; -.
DR   OrthoDB; EOG9C5G3M; -.
DR   PhylomeDB; Q8TD94; -.
DR   NextBio; 83560; -.
DR   ArrayExpress; Q8TD94; -.
DR   Bgee; Q8TD94; -.
DR   CleanEx; HS_KLF14; -.
DR   Genevestigator; Q8TD94; -.
DR   GermOnline; ENSG00000174595; Homo sapiens.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045449; P:regulation of transcription; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 1.
DR   Pfam; PF00096; zf-C2H2; 2.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE   1: Evidence at protein level;
KW   Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW   Phosphoprotein; Polymorphism; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN         1    323       Krueppel-like factor 14.
FT                                /FTId=PRO_0000047186.
FT   ZN_FING     195    224       C2H2-type 1.
FT   ZN_FING     225    254       C2H2-type 2.
FT   ZN_FING     255    282       C2H2-type 3.
FT   MOD_RES     237    237       Phosphothreonine.
FT   VARIANT     173    173       A -> P (in dbSNP:rs35770036).
FT                                /FTId=VAR_052718.
FT   CONFLICT     47     47       H -> Q (in Ref. 2; ABF82392/ABF82393).
SQ   SEQUENCE   323 AA;  33124 MW;  D9129E7968E598A3 CRC64;
     MSAAVACLDY FAAECLVSMS AGAVVHRRPP DPEGAGGAAG SEVGAAHPES ALPGPGPSGP
     ASVPQLPQVP APSPGAGGAA PHLLAASVWA DLRGSSGEGS WENSGEAPRA SSGFSDPIPC
     SVQTPCSELA PASGAAAVCA PESSSDAPAV PSAPAAPGAP AASGGFSGGA LGAGPAPAAD
     QAPRRRSVTP AAKRHQCPFP GCTKAYYKSS HLKSHQRTHT GERPFSCDWL DCDKKFTRSD
     ELARHYRTHT GEKRFSCPLC PKQFSRSDHL TKHARRHPTY HPDMIEYRGR RRTPRIDPPL
     TSEVESSASG SGPGPAPSFT TCL
//